Dyadic International, Inc. (NYSE:DIL)
Industry: Healthcare

Listed 3 Consecutive Market Days. On List as of 03/07/2006 Through 03/10/2006

Dyadic International, Inc. (Dyadic) is a biotechnology company, a developer and distributor of specialty enzymes and related products for sale to the textile, food, animal feed, starch, pulp and paper and other industries. The Company is focused on functional proteomics through the discovery, development and manufacturing of products, including enzymes and proteins, derived from the genes of complex living organisms (including humans) found in the earth's biodiversity. Using its platform technologies for gene discovery and gene expression, Dyadic is developing additional biological products (such as proteins, enzymes, polypeptides and small molecules) for use by itself and for applications in large segments of the agricultural, energy, industrial, chemical and pharmaceutical industries. It is based in Jupiter, Florida, with operations in the United States of America, Hong Kong and mainland China, Poland and The Netherlands. Dyadic has developed and used fungal strains to produce enzymes and other biomaterials, but the one on which it has principally focused is a system for protein production, or protein expression, which the Company calls the C1 Expression System. This System is based on its Chrysosporium lucknowense fungus, known as C1, as its host production organism. Enzyme Business The Enzyme Business addresses needs in diverse industrial enzyme markets, including textiles, animal feed, pulp and paper, starch, food, beverage and brewing and other markets. In May 2005, the Company obtained a DNA sequence of the 38,000,000 bases in the C1 genome, which was performed for the Company by Agencourt Bioscience Corporation. The C1 genome sequence is permitting the Company to mine it to identify protein products for a broad spectrum of industries, including energy, animal feed, food, and pulp and paper. Dyadic is developing, manufacturing and marketing cellulase enzymes for a variety of textile production and fabric finishing applications, including softening, fading and treating of denim garments. The Company offers a range of cellulase enzyme products for applications, such as denim finishing where cellulases are used to soften and fade the denim fabric, including Rocksoft ACE series and numerous other Rocksoft series, and biofinishing of cotton and cellulosics using BioACE series, which is a biofinishing process to prevent pilling and improve smoothness, softness and color brightness, and biopolishing. An example of a cellulosic fabric is Tencel, a high-performance cellulosic fiber made by Acordis. Its BioACE series, an acid cellulase derived from Trichoderma longibrachiatum, offers a cellulase that has been recommended by Acordis for the treatment of 100% Tencel and its blends. The Company's textile enzymes are formulated in various forms, including granular, liquid and powder. During the year ended December 31, 2003, using its C1 Expression System, Dyadic launched two new products, created by isolating genes and reintroducing them into its C1 host organism. One of its products, NCE2X, replaced one of the Company's standard neutral cellulase products. Dyadic serves the pulp and paper industry market by developing, producing and selling enzymes for bleach boosting, de-inking, bio-refining and wastewater processes. It offers four commercial products: FibreZyme LBL for bleach boosting, FibreZyme LDI for de-inking, FibreZyme LBR for bio-refining and FibreZyme LWT for Wastewater Treatment. The Company is in the preliminary stages of testing a new bio-refining product. Dyadic provides specialty enzymes for customers who process grains, such as barley, wheat and rye to produce animal feed and other related products. The Company makes and sells two animal feed enzyme products offered in different activity levels and formats: its Beta Glucanase BP CONC, a beta-glucanase, is used in conjunction with barley-based diets, and its Xylanase 2XP CONC, a xylanase, is used in conjunction with wheat-based diets. Dyadic produces and sells the product CeluStar XL to the wheat starch processing plants in Europe for the pr

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