Northstar Neuroscience, Inc., a development stage company, focuses on the development and commercialization of neuromodulation theraphies for neurological diseases and disorders. Its Renova cortical stimulation system, an investigational device, delivers targeted electrical stimulation to the cortex, the outermost layer of the brain, in cortical stimulation process. The company evaluates its investigating cortical stimulation therapy for the treatment of treatment resistant depression, stroke related upper extremity hemiparesis, and tinnitus using its Renova system. Northstar Neuroscience was founded in 1999 and is headquartered in Seattle, Washington.